About

Dr. Avriel Linane, D.O., is a board certified neurologist, with specialty training in Epilepsy, who delivers comprehensive and compassionate care to her patients and their families. She cares for men and women with a broad spectrum of neurologic diseases including seizures, headaches, dementia, neuropathic pain, stroke, tremor, and other disorders of the brain, spinal cord and peripheral nervous system.  Dr. Linane uses a patient centered approach to guide patients in understanding their disease and being involved in the decision-making process for treatment plans and goals. She joined SCNC in 2015, and provides care to patients in the outpatient clinic, as well as in the hospital at Huntington Memorial. Given her two year fellowship training in Epilepsy and Neurophysiology, she is also involved in monitoring brain and spinal cord surgeries (intraoperative monitoring), detecting seizure activity by reading routine and long-term EEGs, and managing the complexities of refractory epilepsy with medication optimization, life style modifications, and evaluation for surgical epilepsy treatments.  

EDUCATION

• Neurophysiology / Epilepsy Fellowship, Vanderbilt University, Nashville, TN, July 2013 – 2015 

• Resident in Department of Neurology, University of California, Irvine Medical Center, Orange, CA, July 2010 – 2013

• Internship in Department of Internal Medicine, University of California, Irvine Medical Center, Orange, CA, July 2009 – 2010

• Doctor of Osteopathic Medicine [Cum Laude], Lake Erie College of Osteopathic Medicine, Bradenton, FL, Aug. 2005 – June 2009  

• Bachelor of Science [Cum Laude], Degrees in Biology and Psychology, University of Washington, Seattle, WA, Sep. 2000 – June 2005

BOARD CERTIFICATION

• American Board of Psychiatry and Neurology, Subspecialty Epilepsy, October 2016

• American Board of Psychiatry and Neurology, September 2014

PUBLICATIONS

• Avriel Linane, Andre Lagrange, Cary Fu, Bassel Abou-Khalil (2015). Generalized onset seizures with focal evolution (GOFE)- A unique seizure type in the setting of generalized epilepsy. Epilepsy and Behavior 54, 20-29. [Pubmed Link]

• Torgerson, T., Linane, A., et al. (2007) Severe food Allergy as a Variant of IPEX Syndrome Caused by a Deletion in a Non-Coding Region of the FOXP3 Gene. Gastroenterology 132 (5): 1705-1717. [Pubmed Link]

CLINICAL TRIALS

• Protocol N01199
  An Open-Label, Multicenter, Follow-Up Trial to Evaluate the Long-Term Safety and Efficacy of  Brivaracetam used as Adjunctive Treatment at a Flexible Dose up to a Maximum of 100mg/day in Subjects 16 Years or Older Suffering from Epilepsy (NCT00175916).
  Primary Investigator: Bassel Abou-Khalil, M.D.
  Role: Sub-Investigator

• Protocol #P261-401
  A Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Intranasal Midazolam (USL261) in the Outpatient Treatment of Subjects with Seizure Clusters (NCT01390220).
  Primary Investigator:  Bassel Abou-Khalil, M.D.
  Role: Sub-Investigator

• Protocol CEMC101.01
  Utility of Intravenous Lacosamide Compared with Fosphenytoin in the Treatment of Patients with Frequent Non-convulsive Seizures (NCT01458522).
  Primary Investigator:  Amir Arain, M.D.
  Role:  Sub-Investigator

• Protocol VRX-RET-E22-303
  A multicenter, Open-Label, Long-Term, Safety, Tolerability and Efficacy Study of Retigabine in Adult Epilepsy Patients with Partial-Onset Seizures
  Primary Investigator:  Bassel Abou-Khalil, M.D.
  Role:  Sub-Investigator